EC Number   |
Inhibitors |
Structure |
|---|
    1.11.1.11 | 2,2,6,6-tetramethylpiperidinyl-1-oxide |
formation of 2,2,6,6-tetramethylpiperidinyl-1-oxy-adducts and subsequent oxidation of the cysteine residue located near the propionate group of heme leads to loss of enzyme activity |
   |
| 1.11.1.11 | 2,2,6,6-tetramethylpiperidinyl-1-oxyl radical |
formation of 2,2,6,6-tetramethylpiperidinyl-1-oxy-adducts and subsequent oxidation of the cysteine residue located near the propionate group of heme leads to loss of enzyme activity |
|
| 1.11.1.11 | 2,6-dichloroisonicotinic acid |
54% inhibition at 0.1 mM, 95% inhibition at 1 mM, the inhibition is not time-dependent |
|
| 1.11.1.11 | 2,6-dihydroxybenzoic acid |
biologically active, 72% inhibition at 0.2 mM |
|
| 1.11.1.11 | 2-mercaptoethanol |
enzyme form C: 50% inhibition at 5 mM, 6 min, 100% inhibition after 18 min |
|
| 1.11.1.11 | 2-mercaptoethanol |
not inhibitory at 0.5 mM, 31% inhibition at 5 mM |
|
| 1.11.1.11 | 2-mercaptoethanol |
70.3% activity remaining at 1 mM |
|
| 1.11.1.11 | 2-nitrobenzoic acid |
1.48% activity remaining at 1 mM |
|
| 1.11.1.11 | 3,3'-dithiobis(6-nitrobenzoic acid) |
5 mM, 80% residual activity, APX 1, 24% residual activity, APX 2 |
|
| 1.11.1.11 | 3,5-dichlorosalicylic acid |
biologically active, 59% inhibition at 0.2 mM |
|
