EC Number |
Inhibitors |
Structure |
---|
1.1.1.37 | (E)-3-(4-((3R,5R,7R)-adamantan-1-yl)phenoxy)-N-(5-(piperidine-1-carbonyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl) acrylamide |
- |
|
1.1.1.37 | (NH4)2SO4 |
reduction of oxaloacetate to malate and oxidation of malate to oxaloacetate |
|
1.1.1.37 | (S)-malate |
product inhibition, 66% inhibition at 5 mM |
|
1.1.1.37 | (S)-malate |
substrate inhibition, 60% inhibition at 30 mM |
|
1.1.1.37 | (S)-malate |
product inhibitor |
|
1.1.1.37 | (S)-malate |
24.2% substrate inhibition at 20 mM |
|
1.1.1.37 | (S)-malate |
at 1 mM |
|
1.1.1.37 | 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one |
i.e. differentiation-inducing factor DIF-1, a morphogen secreted from Dictyostelium discoideum, inhibits proliferation of several cancer cells via suppression of the Wnt/beta -catenin signaling pathway, specifically to mMDH and inhibits its activity, no binding of cytosolic MDH, overview |
|
1.1.1.37 | 11-chloro-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one |
65.3% inhibition at 0.010 mM |
|
1.1.1.37 | 2',3'-Cyclic AMP |
- |
|