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Results 1 - 10 of 33 > >>
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EC Number Inhibitors Commentary Structure
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2more inhibitor structure-function relationship and molecular docking Go to the Ligand Summary Page
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2more inhibitor structure-function realtionship and molecular docking Go to the Ligand Summary Page
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2more design, synthesis and biochemical evaluation of inhibitor 4 based on the putative transition-state (TS) for the isochorismatase partial reaction of MbtI. The inhibitor mimics the hypothesized charge build-up at C-4 of chorismate in the TS as well as C-O bond-formation at C-6. Another important design element of the inhibitor is replacement of the labile pyruvate side-chain in chorismate with a stable C-linked propionate isostere. Development of a stereocontrolled synthesis of the highly functionalized cyclohexene inhibitor that features an asymmetric aldol reaction using a titanium enolate, diastereoselective Grignard addition to a tert-butanesulfinyl aldimine, and ring closing olefin metathesis as key steps Go to the Ligand Summary Page
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2Mg2+ above 1 mM Go to the Ligand Summary Page
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2Cu2+ - Go to the Ligand Summary Page
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2EDTA - Go to the Ligand Summary Page
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2Hg2+ - Go to the Ligand Summary Page
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2K+ - Go to the Ligand Summary Page
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2NEM - Go to the Ligand Summary Page
Show all pathways known for 5.4.4.2Display the word mapDisplay the reaction diagram Show all sequences 5.4.4.2salicylic acid treatment of plants suppresses the enhancement of enzyme expression by O3 Go to the Ligand Summary Page
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