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Search Inhibitors

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EC Number
Inhibitors
Commentary
Structure
(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-P-CH2-PP
compound is converted to an analogue of the MoaC reaction intermediate and causes mechanism-based inhibition. the reaction product harbors an acid-labile triaminopyrimidinone base without an established pyranopterin structure and forms a tight complex with MoaC likely through a covalent linkage
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