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Results 1 - 10 of 54 > >>
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EC Number Inhibitors Commentary Structure
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.36more 2-amino-4-oxo-4-phenylbutanoate inhibitors are unstable in solution and eliminate to form the corresponding 4-oxo-4-phenylbut-2-enoates that then react with CoA in situ to form nanomolar inhibitors of MenB. The potency of these compounds results from interaction of the CoA adduct carboxylate with the MenB oxyanion hole, a conserved structural motif in the crotonase superfamily. No inhibition by 1548L21 at 0.3 mM Go to the Ligand Summary Page
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.36more little or no inhibition by dimethylamide Go to the Ligand Summary Page
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.36succinyl-CoA - Go to the Ligand Summary Page
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.363-hydroxybutyryl-CoA - Go to the Ligand Summary Page
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.36pantothenic acid - Go to the Ligand Summary Page
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.36salicylyl-CoA - Go to the Ligand Summary Page
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.362,3-dihydroxybenzoyl-CoA - Go to the Ligand Summary Page
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.36pimelic acid - Go to the Ligand Summary Page
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.362,4-dihydroxybenzoyl-CoA - Go to the Ligand Summary Page
Show all pathways known for 4.1.3.36Display the word mapDisplay the reaction diagram Show all sequences 4.1.3.36methyl (2Z)-(2-oxo-2H-1,4-benzoxazin-3(4H)-ylidene)ethanoate - Go to the Ligand Summary Page
Results 1 - 10 of 54 > >>
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