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Results 1 - 10 of 29 > >>
EC Number
Inhibitors
Commentary
Structure
actin
-
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Aki1
-
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astrin
-
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Cdc55
results suggest that Cdc55 acts as inhibitor downstream from shugoshin
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Cdk1 kinase
phosphorylation-dependent binding of the cyclin B1 subunit of Cdk1 kinase to a Cdc6-like domain of separase inhibits separase
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cyclin B
-
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cyclin B1
-
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cyclin-dependent kinase 1-cyclin B1
Cdk1-cyclin B1 triggers precipitation of separase by phosphorylation but stabilizes it by inhibitory binding. Only separase that is first complexed by Cdk1-cyclin B1 can later be activated by cyclin B1 degradation
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more
nuclear exclusion of separase might provide the means to preclude cohesin cleavage at telophase and G1 stage of the cell cycle
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more
cohesin cleavage is inhibited by a PP2ACdc55-dependent mechanism
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Results 1 - 10 of 29 > >>