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EC Number
Inhibitors
Commentary
Structure
3.1.2.22
1-palmitoyl lysophosphatidylcholine
competitive inhibitor for acylprotein thioesterase activity
3.1.2.22
Chloroquine
inhibits the hydrolysis and leads to accumulation of lipid cysteine thioesters in the lysosomes of treated cells
3.1.2.22
Didemnin B
-
3.1.2.22
diethyl dicarbonate
-
3.1.2.22
dithiothreitol
-
3.1.2.22
KCl
-
3.1.2.22
leupeptin
inhibits the hydrolysis and leads to accumulation of lipid cysteine thioesters in the lysosomes of treated cells but has no direct inhibitory effect on the enzyme
3.1.2.22
more
no inhibition by EDTA
3.1.2.22
more
dSmt3 mutations are the lone suppressor modifiers
3.1.2.22
NaCl
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