EC Number   |
Inhibitors |
Structure  |
|---|
    2.3.1.54 | more |
the putative pyruvate formate-lyase deactivase, as activity of AdhE together with an alcohol dehydrogenase and an acetaldehyde-CoA dehydrogenase activities, is not active on the enzyme PFL, it has no PFL deactivating activity |
 |
| 2.3.1.54 | ATP |
regulates pyruvate cleavage to acetyl-CoA and formate, 10 mM reduces the reactin velocity by 95% |
  |
| 2.3.1.54 | ATP |
- |
|
| 2.3.1.54 | ADP |
- |
|
| 2.3.1.54 | CoA |
inhibits exchange reaction between pyruvate and formate, inhibits formate formation from pyruvate above 0.075 mM |
|
| 2.3.1.54 | S-adenosyl-L-homocysteine |
- |
|
| 2.3.1.54 | 2-mercaptoethanol |
rapid, reversible inactivation, deactivation is a non-destructive transfer of an H atom equivalent to quench the glycyl radical |
|
| 2.3.1.54 | iodoacetate |
- |
|
| 2.3.1.54 | formate |
product inhibition |
|
| 2.3.1.54 | Cl- |
- |
|
