EC Number   |
Inhibitors |
Structure |
|---|
    1.1.1.365 | N-ethylmaleimide |
84% residual activity at 1 mM |
   |
| 1.1.1.365 | L-gulonate |
competitive inhibitor, Ki in the low mM range |
|
| 1.1.1.365 | L-gulono-1,4-lactone |
competitive inhibitor, Ki in the low mM range |
|
| 1.1.1.365 | C-4 epimer galacturonate |
displays marked substrate inhibition |
|
| 1.1.1.365 | NADP+ |
mutant enzyme R267L shows a considerable sensitivity at the lower (0.16 mM) but not at the higher (0.8 mM) NADH concentration |
|
| 1.1.1.365 | more |
substrate inhibition by aldonic acids. The products L-galactonate and L-galactono-1,4-lactone are observed to mitigate substrate inhibition by galacturonate, with the lactone having a greater effect than the acid |
|
| 1.1.1.365 | glucuronate |
weak substrate inhibition |
|
