EC Number |
Inhibitors |
Structure |
---|
3.4.23.20 | methyl cyclo[(2S)-2-[[(1R)-1-(N-(l-N-(3-methylbutanoyl)valyl-L-aspartyl)amino)-3-methylbutyl]hydroxyphosphinyloxy]-3-(3-aminomethyl)] phenylpropanoate |
phosphonate-based macrocycle PPi4, macrocyclic pentapeptide inhibitor |
|
3.4.23.20 | methyl cyclo[(2S)-2-[[(1R)-1-(N-(l-N-(3-methylbutanoyl)valyl-L-aspartyl)amino)-3-methylbutyl]ydroxyphosphinyloxy]-3-(3-aminomethyl)] phenylpropanoate |
- |
|
3.4.23.20 | Mg2+ |
31% residual activity at 10 mM |
|
3.4.23.20 | Mn2+ |
98% residual activity at 10 mM |
|
3.4.23.20 | more |
benzyloxycarbonyl-Phe; not: benzyloxycarbonyl-Tyr; p-bromophenacylbromide |
|
3.4.23.20 | more |
p-bromophenacylbromide |
|
3.4.23.20 | more |
chelating agents; potato inhibitor |
|
3.4.23.20 | more |
investigation of the protonation state penicillopepsin in complex with phosphinate and phosphonate inhibitors |
|
3.4.23.20 | more |
not inhibited by phenylmethylsulfonyl fluoride |
|
3.4.23.20 | more |
not inhibited by EDTA and iodoacetic acid |
|