EC Number |
Inhibitors |
Structure |
---|
3.4.22.55 | benzyloxycarbonyl-VDVAD-fluoromethylketone |
- |
|
3.4.22.55 | biotinylated VAD-fluoromethylketone |
irreversible pan-caspase inhibitor |
|
3.4.22.55 | bVAD-fmk |
- |
|
3.4.22.55 | calcium/calmodulin regulated protein kinase II |
phosphorylates caspase-2 at Ser-135 |
|
3.4.22.55 | calcium/calmodulin-dependent kinase II |
- |
|
3.4.22.55 | Cbzl-VDVAD-fluoromethylketone |
caspase-2 cleaves BID in response 16 to endoplasmic reticulum stress. Resistance to endoplasmic reticulum stress-induced apoptosis can be conferred by inhibiting caspase-2 activity |
|
3.4.22.55 | coenzyme Q10 |
- |
|
3.4.22.55 | cyclin-dependent kinase 1 |
- |
|
3.4.22.55 | cyclin-dependent protein kinase1/cyclin B1 |
- |
|
3.4.22.55 | glucocorticoid modulatory element-binding protein 1 |
GMEB1, endogenous inhibitor of pro-caspase-2 activation |
|