EC Number   |
Inhibitors |
Structure |
|---|
    2.8.1.2 | alpha-ketoglutarate |
uncompetitive inhibitor with respect to 3-mercaptopyruvate, 50% inhibition at 9.5 mM |
   |
| 2.8.1.2 | cyanide |
inhibits at short-time intervals, slight enhancement at longer periods |
|
| 2.8.1.2 | cysteamine |
slight |
|
| 2.8.1.2 | cysteine |
- |
|
| 2.8.1.2 | dithiothreitol |
inhibits from 3 mM to 4 mM at a 3-mercaptopyruvate concentration of 15 mM |
|
| 2.8.1.2 | ethylene |
fumigation with ethylene decreases activity to less than 50% |
|
| 2.8.1.2 | glutathione |
- |
|
| 2.8.1.2 | hydrogen peroxide |
together with stoichiometric concentration of tetrathionate, renaturation by dithiothreitol or thioredoxin. Excess molar ratio of hydrogen peroxide inactivates |
|
| 2.8.1.2 | hydrogen peroxide |
hydrogen peroxide (0.1-0.5 mM) causes a concentration-dependent decrease in the activity of recombinant enzyme (54% inhibition at 0.1 mM, 87% inhibition at 0.5 mM) |
|
| 2.8.1.2 | hydrogen peroxide |
strong inhibition |
|
