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EC Number
Inhibitors
Commentary
Structure
2.3.1.39
diethyldicarbonate
inhibits MCT1 but not MCT2 at 1 mM
2.3.1.39
EDTA
63% inhibition at 1 mM, complete inhibition at 10 mM
2.3.1.39
iodoacetamide
malonyl-CoA protects; pH-dependent
2.3.1.39
iodoacetamide
-
2.3.1.39
iodoacetamide
59% inhibition at 0.1 mM
2.3.1.39
iodoacetate
-
2.3.1.39
isoniazid
acts synergistically with trifluoroperazine
2.3.1.39
magnoflorine
-
2.3.1.39
malonyl-CoA
inhibition of MCT1 at 0.01 mM and inhibition of both isozymes at 0.02 mM and 0.04 mM; inhibits both MCT1 and MCT2
2.3.1.39
methylmalonyl-CoA
inhibition of MCT1 at 0.1 mM
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