EC Number   |
Inhibitors |
Structure |
|---|
    1.1.1.3 | L-phenylalanyl-5-hydroxy-4-oxo-L-norvaline |
i.e. (S)-2-N-[(S)-phenylalanyl]amino-5-hydroxy-4-oxopentanoic acid |
   |
| 1.1.1.3 | L-valyl-5-hydroxy-4-oxo-L-norvaline |
i.e. (S)-2-N-[(S)-valyl]amino-5-hydroxy-4-oxopentanoic acid |
|
| 1.1.1.3 | more |
inhibitor docking study, overview |
|
| 1.1.1.3 | more |
L-homoserine inhibits the activity of aspartokinase encoded by metL |
|
| 1.1.1.3 | more |
L-homoserine oxidation of the Thermotoga maritima enzyme is almost impervious to inhibition by L-threonine, while L-threonine inhibits AK activity in a cooperative manner. The distinctive sequence of the regulatory domain in Thermotoga maritima AK-HseDH is likely responsible for the unique sensitivity to L-threonine. The quaternary structure of this enzyme is not affected by L-threonine |
|
| 1.1.1.3 | more |
Lys, Met, and S-2-aminoethyl-L-cysteine do not affect HSDH activity at 1-5 mM |
|
| 1.1.1.3 | itraconazole |
MIC value against strain Pb18 is 0.007 mg/ml |
|
| 1.1.1.3 | Amphotericin B |
MIC value against strain Pb18 is 0.06 mg/ml |
|
| 1.1.1.3 | Amphotericin B |
MIC value against strain Pb18 is 0.12 mg/ml |
|
| 1.1.1.3 | Zinc203432 |
MIC value is 0.032 mg/ml |
|
