EC Number |
General Stability |
Reference |
---|
6.2.1.5 | 25% loss of activity after 3 months at 4°C, immobilized enzyme |
814 |
6.2.1.5 | ATP or phosphate protects against trypsin inactivation |
809 |
6.2.1.5 | mutant W76F and mutant W43,76,248F are more sensitive to proteolysis by clostripain than the wild type enzyme or other Trp mutant proteins. ADP and ATP both protect the enzyme against inactivation by clostripain. Mutagenic replacement of Argbeta80, but not Argbeta14, with Lys results in an enzyme that is resistant to clostripain as wild type enzyme |
824 |
6.2.1.5 | phosphorylation of 1 active site histidine residue per oligomeric enzyme molecule results in a significant change in the three-dimensional structure of the enzyme to a tighter conformation, with concomittant stability |
809 |