EC Number   |
General Stability |
Reference |
|---|
    4.1.1.23 | 1-ribosyloxipurinol 5'-phosphate prevents loss of activity during preincubation in absence of substrate, when the inhibitor concentration is high enough to inhibit the enzyme substantially |
4169 |
| 4.1.1.23 | Asp-70 makes a crucial contribution to enzyme stability |
650145 |
| 4.1.1.23 | conversion of the monomer to higher molecular weight forms is associated with increased stability |
4171 |
| 4.1.1.23 | glycerol, 50% v/v is an effective stabilizer of the orotidine-5'-phosphate decarboxylase domain at 4°C, -20°C or -70°C |
4180 |
| 4.1.1.23 | NaCl stabilizes the dimeric active enzyme form |
649921 |
| 4.1.1.23 | orotidine 5'-phosphate and UMP stabilize |
651345 |
| 4.1.1.23 | unliganded enzyme without bound UMP or OMP forms heavy precipitates during purification |
653646 |
| 4.1.1.23 | unstable to repeated freezing and thawing |
4172 |
