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EC Number General Stability Reference
Show all pathways known for 1.1.1.82Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.82a small carboxy-terminal peptide of the native enzyme is accessible to proteolytic degradation followed by activation of the inactive oxidized enzyme. This peptide is involved in the regulation of activity, tetramer formation and thioredoxin binding 287392
Show all pathways known for 1.1.1.82Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.82denaturation by 2 M guanidine-HCl 287392
Show all pathways known for 1.1.1.82Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.82no effect of guanidine/HCl up to 0.25 M on the quarternary structure of the enzyme in its oxidized and reduced form. In the oxidized state the enzyme undergoes guanidine-dependent dissociation to the monomer with a midpoint of transition at 0.5 M. The kinetic of unfolding is significantly faster for the reduced than for the oxidized enzyme 287389
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