EC Number   |
Activating Compound |
Reference |
|---|
   7.2.2.3 | angiotensin II |
angiotensin II has an activating and regulatory role for Na+-ATPase activity in healthy rats, and angiotensin II links the enzyme activity to hypertension in spontaneously hypertensive rats, where it has an inhibitory effect on Na+-ATPase activity. Ang II interacts with different receptors in spontaneously hypertensive rats and WKY wild-type rats |
711297 |
| 7.2.2.3 | angiotensin II |
physiological activation at femtomolar concentration. The activation by angiotensin II is completely abolished in the adult progeny of rats that are undernourished during lactation |
720830 |
| 7.2.2.3 | angiotensin II |
stimulates the proximal tubule Na+-ATPase through the AT1 receptor/phosphoinositide phospholipase Cbeta/protein kinase C pathway, molecular mechanisms, overview. Ang II induces fast and correlated activation of Na+-ATPase and PKC activities with the maximal effect of 115% activation observed at 1 min and sustained for 30 min. Involvement of phospholipase A2, PLA2, on the modulation of Na+-ATPase activity by Ang II, and modulation of the effect of Ang II on Na+-ATPase activity by PLA2 inhibitors, e.g. quinacrine, PACOCF3 and a specific inhibitor, BEL, overview |
711296 |
| 7.2.2.3 | angiotensin II |
stimulates the renal Na+-ATPase, reversed by Ang-(1-7) via MAS and the A779-sensitive MAS receptor in a Gs/PKA pathway, molecular mechanism, overview |
711011 |
| 7.2.2.3 | ATP |
ATPase activity increases as ATP increased and the activity is saturated at about 6 mM ATP |
719166 |
| 7.2.2.3 | bile salt |
induction of enzyme expression and increase in enzymic activity with concomitant decrease in intracellular ATP levels. In a bile salt-resistant mtant strain, tolerance of acidic pH-value is better than in parent strain. Expression and activity of enzyme are increased in the mutant |
668431 |
| 7.2.2.3 | Ca2+ |
67% activity after addition of EGTA |
695869 |
| 7.2.2.3 | carbonyl cyanide m-chlorophenyl hydrazine |
- |
719166 |
| 7.2.2.3 | carbonyl cyanide p-chlorophenylhydrazone |
- |
210466 |
| 7.2.2.3 | carbonyl cyanide p-trifluoromethoxyphenylhydrazone |
- |
210458 |
