EC Number   |
Activating Compound |
Reference |
|---|
    6.3.4.5 | IL-1beta |
ASS is rapidly induced by a short time exposure of IL-1beta to Caco-2 cells. By contrast, a long-term 24 h exposure to IL-1beta inhibited the ASS activity despite an increase in both specific mRNA-level and protein amount, demonstrating a post-translational effect |
672445 |
| 6.3.4.5 | lipopolysaccharide |
argininosuccinate synthase accumulates in circulation within 1 h after treatment with both lipopolysaccharide alone and hepatotoxic combination of lipopolysaccharide and D-Galactosamine. Enzyme physically binds to lipopolysaccharide |
715188 |
| 6.3.4.5 | more |
AS mRNA is 4-6fold induced by Escherichia coli lipopolysaccharide and mouse interferon-gamma, kinetics of induction |
653186 |
| 6.3.4.5 | more |
AS mRNA is induced by Escherichia coli lipopolysaccharide and mouse interferon-gamma |
653186 |
| 6.3.4.5 | more |
CRE-1 is the cis-element responsible for liver-specific cAMP induction of the human ASS gene |
690768 |
| 6.3.4.5 | more |
expression of argininosuccinate synthetase mRNA is inducible by lipopolysaccharides |
653344 |
| 6.3.4.5 | more |
inducible enzyme, immunostimulation of AS synthesis with lipopolysaccharide or cytokines, such as TNF-alpha, interleukin 1 and interferon-gamma |
653046 |
| 6.3.4.5 | more |
interaction with Bj-BPP-10c, snake venom anti-hypertensive peptide of Botrops jararaca, activates the catalytic activity of argininosuccinate snythetase in a dose-dependent manner |
704509 |
| 6.3.4.5 | more |
study of the effect of recombinant mycoplasma arginine deiminase on cell proliferation, good correlation of the resistance to this treatment with the AS activity in the cell lines |
650761 |
| 6.3.4.5 | more |
troglitazone, a PPARgamma ligand, and thiazolidinedione up-regulate vascular endothelial argininosuccinate synthase expression, quantitative real time RT-PCR, overview |
690727 |
