EC Number |
Activating Compound |
Reference |
---|
5.6.1.2 | acetate |
2fold activation, maximum between 0.5 and 0.7 M |
247027 |
5.6.1.2 | axonemes |
salt-extracted axonemes cause a 7 to 8fold activation of 21S dynein, maximum activation with axoneme/dynein weight ratio 14/1, low ionic strength, pH 7.9-8.3 |
247018 |
5.6.1.2 | Calmodulin |
10fold activation of 14S dynein, about 0.01 mM free Ca2+, half-maximal activation at about 0.0001 mM calmodulin |
247035 |
5.6.1.2 | Calmodulin |
from porcine brain, 3-to 8fold |
247021 |
5.6.1.2 | Cl- |
more than 15fold activation between 0 and 1.0 M |
247027 |
5.6.1.2 | KCl |
concentrations of 0.2 to 0.4 M stimulate enzyme activity 1.4 to 1.6fold |
247014 |
5.6.1.2 | KCl |
linear increase in the range of 0.1 M and 0.6 M KCl |
247018 |
5.6.1.2 | Lactate |
2fold activation, maximum between 0.5 and 0.7 M |
247027 |
5.6.1.2 | Lis1 |
stimulates the average in vitro enzymatic activity of dynein by 40%. A subpopulation of brain dynein binds Lis1. ATPase activity is substantially higher for dynein motors that interact with Lis1. It is proposed that modulation of the Lis1-dynein-interaction serves as a control point in motor regulation |
669949 |
5.6.1.2 | Lys-Phe-Gly-Val-Gly-Phe-Lys |
- |
735303 |