EC Number   |
Activating Compound |
Reference |
|---|
   5.6.1.1 | 3-[[3-(methylsulfanyl)phenyl]amino]-4-[4-(trifluoromethyl)phenyl]-1H-pyrrole-2,5-dione |
accelerates KSP-catalyzed ATP hydrolysis in the absence of microtubules circa 10fold |
687306 |
| 5.6.1.1 | microtubule |
- |
675519, 689644 |
| 5.6.1.1 | microtubules |
SPAS-1's ATPase activity increases with increasing concentrations of microtubules up to 0.00025 mM and then declines at higher microtubule concentrations. In the presence of 0.00025 mM microtubules, ATPase activity is 7times higher than in the absence of microtubules |
712104 |
| 5.6.1.1 | more |
high levels of P60-katanin during development |
699690 |
| 5.6.1.1 | more |
overexpression of katanin results in 12% loss of microtubule mass, low degradation of microtubule array in katanin-overexpressing neurons |
700089 |
| 5.6.1.1 | more |
overexpression of spastin result in 30% loss of microtubule mass, increase in axonal branching in spastin-overexpressing neurons, degrade of microtubule array in spastin-overexpressing neurons |
700089 |
| 5.6.1.1 | p80 KAT3p |
dual character of p80 KAT3p as both an activator and a repressor of p60 KAT1p |
748669 |
| 5.6.1.1 | Protein kinase C |
adseverin upregulation is linked to the chondrocyte maturation program and is regulated by PKC |
673239 |
| 5.6.1.1 | tubulin |
at 0.001 mM, up to 6fold stimulation of ATPase activity |
654498 |
