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EC Number Activating Compound Commentary Reference
Show all pathways known for 5.3.1.9Display the word mapDisplay the reaction diagram Show all sequences 5.3.1.9Zn2+ the coordination shell of Zn2+ changes significantly from the initial static crystal conformation to the equilibrated state of the enzyme-D-fructose 6-phosphate complex. Although Zn2+ is not directly involved in the reaction, the metal ion as a structural anchor constructs a hydrogen bond wire to connect the substrate to the outer region, providing a potential channel for hydrogen exchange between the substrate and solvent 722445
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