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Activating Compound
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5.2.1.8
ATP
at least 3fold stimulation, excess of ATP over Mg2+ is inhibitory
662459
5.2.1.8
ATP
stimulation
662459
5.2.1.8
equine chorionic gonadotropin
significant increase in expression of isoform Pin1 mRNA, application of human chorionic gonadotropin attenuates this increase. mRNA expression of E2F transcription factor, which controls the expression of Pin1, is decreased in the ovaries after treatment with equine chorionic gonadotropin. Protein level of Pin1 shows the same tendencies as the expression of RNA
681633
5.2.1.8
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GM-CSF-induced activation of Erk1/2, which phosphorylated Thr167 of the pro-apoptotic Bcl-2-associated X protein, Bax, facilitates de novo interaction of Bax with the prolyl isomerase Pin1
705854
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