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Results 1 - 10 of 21 > >>
EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19Enhancer glycoprotein bound to the carboxyl propeptide of type I procollagen 31034
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19Enhancer glycoprotein characterization 31043
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19Enhancer glycoprotein enhancer may play a regulatory role in procollagen processing 31043
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19Enhancer glycoprotein enhances activity of C-proteinase 31034, 31036
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19Enhancer glycoprotein stimulates activity 668838
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19Frizzled-related protein secreted Frizzled-related protein sFRP2 serves as a direct enhancer of procollagen C proteinase activity of tolloid-like metalloproteinases. The level of fibrosis, in which procollagen processing by tolloid-like proteinases has a rate-limiting role, is markedly reduced in Sfrp2-null mice subjected to myocardial infarction. This reduced level of fibrosis is accompanied by significantly improved cardiac function 700348
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19heparin stimulation of BMP-1 activity by procollagen C-proteinase enhancer-1 is further increased by the presence of 0.05 mg/ml heparin 712425
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19heparin sulfate in the presence of both procollagen C-proteinase enhancer-1 and heparin or heparan sulfate, the activity of BMP-1 is further stimulated 712425
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19more both PCPE1 and PCPE2 are located in the extracellular matrix, where they facilitate bone morphogenetic protein 1 (BMP1) cleavage of C-terminal procollagen propeptides. PCPE2 and PCPE1 have different tissue distributions and heparin-binding affinities, suggesting a functional divergence. PCPE2 is heavily expressed in heart tissue in contrast to PCPE1. Both PCPE1 and PCPE2 have two CUB (Complement C1r/C1s, Uegf, Bmp1) domains separated by a short linker region, with each domain consisting of about 110 residues containing a beta-sandwich fold that mediates a variety of protein-protein interactions. Phenotype of PCPE2-/- mice, overview 754110
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.19PCPE-1 enhances degredation of procollagen type I 5 fold, enhances C-terminal processing of procollagen type III when this substrate is in its native, disulfide-bonded conformation, has no effect on the in vitro BMP-1 processing of procollagen VII, procollagen V N-propeptide, laminin 5 gamma2 chain, osteoglycin, prolysyl oxidase or chordin 669352
Results 1 - 10 of 21 > >>