EC Number |
Activating Compound |
Reference |
---|
3.4.22.60 | 2-(4-methoxyphenyl)-4-(piperazin-1-yl)quinoline |
9% stimulation of caspase-7 cleavage of TDP-43 at 0.01 mM |
731375 |
3.4.22.60 | 2-(4-methoxyphenyl)-N-[2-(morpholin-4-yl)ethyl]quinolin-4-amine |
4% stimulation of caspase-7 cleavage of TDP-43 at 0.01 mM |
731375 |
3.4.22.60 | apoptosome complex |
- |
669509 |
3.4.22.60 | caspase 1 |
caspase-7 is cleaved and activated by caspase-1. This is mediated by flagellin and requires the host receptors Nlrc4 and Naip5 |
732797 |
3.4.22.60 | ceramide |
- |
670408 |
3.4.22.60 | cytolethal distending toxin |
from Actinobacillus actinomycetemcomitans |
668912 |
3.4.22.60 | etoposide |
- |
669391 |
3.4.22.60 | etoposide |
procaspase-7 cleavage (= activation of caspase-7), which is abrogated in cells with ectopically expressed p53 |
667232 |
3.4.22.60 | FSH |
antiapoptotic effect on granulosa cells and a proapoptotic effect on theca-interstitial cells |
668416 |
3.4.22.60 | gonadotropins |
increases caspase-7 activity in both theca-interstitial cells and granulosa cells |
668416 |