EC Number   |
Activating Compound |
Reference |
|---|
   3.4.22.55 | 2-chloro-2'-deoxyadenosine |
- |
663875 |
| 3.4.22.55 | amyloid beta1-42 |
the levels of activated caspase-2 in cultured hippocampal neurons significantly increase within 30 min of treatment with 0.003 mM amyloid beta1-42 |
731274 |
| 3.4.22.55 | ATM/ATR |
caspase-2 is activated by ATM/ATR independently of p53 when Chk1 activity is repressed |
717458 |
| 3.4.22.55 | caspase-10 |
is required for effective processing of caspase-2 |
666511 |
| 3.4.22.55 | CD95-death-inducing signaling complex |
- |
732592 |
| 3.4.22.55 | cyclin D3 |
- |
663875 |
| 3.4.22.55 | lovastatin |
0.05 mM for 24 h, increases caspase-2 gene expression |
666351 |
| 3.4.22.55 | more |
caspase-2 is activated by dimerization |
717458 |
| 3.4.22.55 | more |
caspase-2 is activated by proximity-induced oligomerization and trans-cleavage in vitro. Caspase-2 activation is possibly also mediated by caspase-8 in the death-inducing signaling complex |
732220 |
| 3.4.22.55 | more |
caspase-2 is rapidly activated by nerve growth factor deprivation |
731274 |
