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Results 1 - 4 of 4
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EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.91more auto-cleavage and NS3 protease activity show an absolute requirement for cysteine residues 1123, 1125 and 1171 within NS3, whereas cysteine 922 (within NS2) is only required for NS2/3 auto-cleavage activity and histidine 1175 is only required for NS3 activity. Complete NS3 protease domain (including the C-terminal alpha-helix) is required for NS2/3 auto-cleavage, whereas activity of the NS3 protease is not essential 681415
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.91more formation of an active protease does not require neither cleavage of NS2B from NS3 nor a free NS3 N-terminus 680760
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.91more presence of basic residues at the P3 and P4 positions significantly promotes reactivity 684956
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.91NS2B viral activator protein 81436
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