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EC Number
Activating Compound
Commentary
Reference
3.4.21.39
enterokinase
-
753380
,
755179
3.4.21.39
heparin
heparin enhances the degradation of the beta-chain of fibrinogen
753116
3.4.21.39
more
chymase has no enzymatic activity under normal physiological conditions, but it is activated immediately after release into the extracellular matrix
700577
3.4.21.39
more
chymase is activated 3fold within 60 min in basal media by scratch wounding cultured monolayers and further potentiated over 10fold at 18 h by additional serum and cytokine treatment, chymase activation is attenuated by inhibition of nitric oxide, superoxide, and peroxynitrite
698854
3.4.21.39
more
high glucose causes a 3fold increase in chymase mRNA level
697785
3.4.21.39
more
the levels of cardiac chymase expression and activity are markedly increased in the hamster hearts in both the control diabetic and insulin-treated diabetic groups as compared with normal hamsters
695395
3.4.21.39
phosphatidylcholine
activates
81368
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