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EC Number
Activating Compound
Commentary
Reference
3.2.1.76
2-mercaptoethanol
-
171555
,
171564
3.2.1.76
dithiothreitol
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171555
,
171564
3.2.1.76
glutathione
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171555
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171564
3.2.1.76
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intracellular IDUA activity increases dose-dependently in both MC3T3-E1 and F665 cells. When laronidase is added to the medium at a low concentration (0.10 mg/ml) there is no difference in the uptake between them. Increase in the enzyme activity is always lower in MC3T3-E1 cells than in F665 ones when laronidase is added to the medium at the concentration of 1.0m g/ml or more, thus uptake of laronidase is lower in MC3T3-E1 cells than in F665 cells
696554
3.2.1.76
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the synthesis of the CnABI3 (ABscisic acid Insensitive3) protein is able to transactivate the IDUA gene expression driven by the arcelin promoter, particularly in the presence of 0.15-0.2 mM (S)-(+)-abscisic acid
682391
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