EC Number   |
Activating Compound |
Reference |
|---|
   3.1.3.53 | KCl |
in organ culture |
681576 |
| 3.1.3.53 | more |
C-terminal leucine-zipper of MYPT 1 subunit is required for cGMP-mediated activation of enzyme |
666095 |
| 3.1.3.53 | more |
P-myosin assembly is essential for SMMP activity |
646352 |
| 3.1.3.53 | more |
rhoA kinase 1 and rhoA kinase 2 isoforms both regulate MLCP phosphorylation |
697357 |
| 3.1.3.53 | more |
telokin facilitates the dissociation of the phosphatase or its catalytic subunit from myosin light chain kinase oligomers increasing the MLCPase activity of the multienzyme complex, but no effect on the activity of the purified MLCPase holoenzyme or its catalytic subunit |
640653 |
| 3.1.3.53 | more |
the activity of the catalytic subunit of MLCP, CSbeta, towards myosin depends on its associated regulatory subunit, namely myosin PPase targeting subunit 1, MYPT1 |
715719 |
| 3.1.3.53 | p116Rip |
RhoA-binding protein, activates enzyme activity of the holoenzyme due to binding to MYPT 1 targeting subunit. Activation is specific to myosin as substrate |
665693 |
| 3.1.3.53 | sodium nitroprusside |
nitrovasodilator, increases MLCP activity in intact carotid media, mechanism |
646362 |
| 3.1.3.53 | type I cGMP-dependent protein kinase |
- |
699117 |
| 3.1.3.53 | U46619 |
thromboxane A2 analogue at 10-7 mol/L, increases phosphorylation of MYPT1 and regulatory myosin light-chain |
679298 |
