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EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.64more enzyme activity is dependent upon the presence of Rpe65 715473
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.64more Rpe65 isomerase activity is strongly stimulated by addition of either 10% phosphatidylglycerol (10.5fold increase of activity) or 10% phosphatidylserine (8.5fold increase of activity) to liposomes containing the same major phospholipids as RPE membranes 715577
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.64more the Cys-112 palmitylation site is essential for the membrane association and activity of RPE65 715501
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.64more the lipid membrane structure is critical for RPE65 enzymatic activity 704711
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.64MYO7A protein the Usher 1B protein MYO7A is required for normal localization and function of the visual retinoid cycle enzyme RPE65. RPE65 normally undergoes a light-dependent translocation to become more concentrated in the central region of the RPE cells. This translocation requires MYO7A 715149
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