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Results 1 - 7 of 7
EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.15celecoxib heterotrophic modulator, switches sulfation from the 3-O-position to the 17beta-O-position and activates such that the total sulfated product exceed product formation by the native enzyme, 3fold to 4fold at 0.25 mM celecoxib 661577
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.15more enzyme induction by 1alpha,25-dihydroxyvitamin D3 via the vitamin D responsive element C/ERB-alpha, but not C/ERB-beta, coactivators p300, steroid receptor coactivator 1 and 2, SRC-1 and SRC-2, but not SRC-3, are also required, overview 675998
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.15more induction of SULT2A1 expression by xenobiotic-activated nuclear receptors pregnane X receptor PXR, constitutive androstane receptor CAR, and the vitamin D3-activated nuclear receptor VDR, aging has no effect on the activity of an IR0 enhancer in the Sult2A1 chromatin to recruit VDR, RXR-alpha, and PXR in mice injected with D3 or PCN 673838
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.15more lithocholic acid induces SULT2A in wild-type and farnesoid X receptor-null mice, chenodeoxycholic acid induces the enzyme only in farnesoid X receptor-null mice, not in wild-type mice, overview 673311
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.15more methotrexate induces SULT2A1 expression via nuclear receptor interactions, molecular mechanism, overview, the constitutive active receptor, CAR, mediates the methotrexate induction of SULT2A1 in both Caco-2 and Hep G2 cells, vitamin D receptor, VDR, also upregulates SULT2A1 gene expression, CAR inhibits VDR-mediated vitaminD3 induction of SULT2A1 but notmethotrexate induction of SULT2A1, overview 674394
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.15more SULT2A1 is a target gene for metabolic regulation/induction by thyroid hormone T3, T3 overexpressing cell s show increased SULT2A1 expression, indirect regulation mechanism via the transcription factor steroidogenic factor 1, SF1, overview 673350
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.15more the enzyme promoter contains composite elements inducible by nuclear receptors pregnane X receptor and constitutive androstane receptor, synergizing effects by HNF4alpha binding at a site near the promoter, overview 676007
Results 1 - 7 of 7