EC Number   |
Activating Compound |
Reference |
|---|
    2.8.1.7 | Anabaena sulfur acceptor E |
in the presence of the Anabaena sulfur acceptor E protein, the catalytic efficiency increases 10fold. For sulfur mobilization, the Anabaena sulfur acceptor E protein partners only SufS and not other cysteine desulfurases from Nostoc sp. |
760523 |
| 2.8.1.7 | dithiothreitol |
activity is strongly dependent on the presence of dithiothreitol, with activity increasing up to 46% when the reductant is present in the reaction mixture. Concentrations higher than 5 mM cause an inhibitory effect |
727067 |
| 2.8.1.7 | dithiothreitol |
increase of enzyme activity at 50 mM |
645621 |
| 2.8.1.7 | frataxin |
frataxin modulates isoform Nfs1m kinetics, increasing Vmax and decreasing the S0.5 value for L-cysteine |
726016 |
| 2.8.1.7 | frataxin |
frataxin or a mutant Fe-S scaffold protein (Isu1Sup) with frataxin-bypassing ability stimulates L-cysteine binding to the enzyme |
738601 |
| 2.8.1.7 | IcsU |
forms disulfide bonds with IcsS and stimulates its activity 6fold |
645638 |
| 2.8.1.7 | Isd11p |
Isd11p is required for the cysteine desulfurase activity of Nfs1p |
724238 |
| 2.8.1.7 | more |
in presence of purified recombinant chloroplast protein CpSufE, Vmax value of cysteine desulfurase CpNifS increases over 40fold and the Km value towards cysteine decreases to half. CpSufE addition decreases the affinity of enzyme for selenocysteine, and a mutant CpSufE lacking the single cysteine is not able to stimulate CpNifS |
674773 |
| 2.8.1.7 | more |
SufE participates in allosteric regulation of the enzyme activity |
738600 |
| 2.8.1.7 | more |
the enzyme requires the presence of sulfurtransferases such as SufE proteins for optimal activity |
737375 |
