EC Number   |
Activating Compound |
Reference |
|---|
   2.7.11.10 | alloferon |
alloferon, a 13-amino acid peptide isolated from the bacteria-challenged larvae of the blow fly Calliphora vicina, activates IKK activity |
694134 |
| 2.7.11.10 | CD28 |
activates Vav-1/IKKalpha and subsequently NFkappaB, meditated by Vav-1 |
662568 |
| 2.7.11.10 | cdc37 |
the chaperone protein associates with the IKK complex and is required for its TNFalpha-induced activation |
671920 |
| 2.7.11.10 | glycogen synthase kinase-3beta |
GSK-3 is required for constitutive IKK activity |
691627 |
| 2.7.11.10 | HSP70 |
the chaperone protein associates with the IKK complex and is required for its TNFalpha-induced activation |
671920 |
| 2.7.11.10 | Hsp90 |
the chaperone protein associates with the IKK complex and is required for its TNFalpha-induced activation |
671920 |
| 2.7.11.10 | human leukemia virus type-1 TAX |
TAX is binding to and activating the IKK complex. A sustained activation of the Tax-mediated activation of the NFkappaB pathway is dependent on an intact Hsp90-IKK complex |
693060 |
| 2.7.11.10 | more |
aldosterone regulates IKKbeta activity by enzyme induction |
662274 |
| 2.7.11.10 | more |
Bcl10 degradation depends on NEMO and CARMA1 |
676906 |
| 2.7.11.10 | more |
cytokine-induced activation of IKK, e.g. by TNFalpha, required for NFkappaB activation, leads to rapid degradation of IkappaB |
662942 |
