EC Number   |
Activating Compound |
Reference |
|---|
    2.3.1.50 | dithiothreitol |
required for enzyme activity |
487164, 487168 |
| 2.3.1.50 | EDTA |
required for enzyme activity |
487168 |
| 2.3.1.50 | etoposide |
- |
487173 |
| 2.3.1.50 | etoposide |
activates enzyme activity, but decreases mRNA level, time-dependent |
487173 |
| 2.3.1.50 | etoposide |
enhanced activity due to chemotherapy with epotoside as therapeutic agent in Molt-4 leukemic cells |
487174 |
| 2.3.1.50 | fenretinide |
up-regulates enzyme activity in neuroblastoma cells |
487174 |
| 2.3.1.50 | more |
enzyme activity is enhanced under stress and in apoptosis, e.g. in pancreatic cells in a model for diabetes, in case of angiotensin II type receptor occupancy |
487174 |
| 2.3.1.50 | more |
increased SPT enzyme activity in reactive astrocytes of the hippocampus at 2 weeks post-kainate injection |
675555 |
| 2.3.1.50 | more |
the enzyme activity and expression in the heart is not affected by high-fat feeding |
676928 |
| 2.3.1.50 | pioglitazone |
increases the enzyme activity in vitro and in vivo independent of standard or high-fat diet |
676928 |
