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EC Number
Activating Compound
Commentary
Reference
2.3.1.26
25-hydroxycholesterol
-
486703
2.3.1.26
25-hydroxycholesterol
activates
486685
,
486689
,
486697
2.3.1.26
25-hydroxycholesterol
not stimulatory
486689
2.3.1.26
25-hydroxycholesterol
stimulates enzyme activity in liver microsomes in vitro with half-maximal stimulation at 0.0168 mM oxysterol. A major part of the activation of microsomal enzyme is not ascribable to increased substrate availability for the enzyme
486701
2.3.1.26
6-ketocholestanol
added at high concentration causes modest increase in enzyme activity
486697
2.3.1.26
7-ketocholesterol
added at high concentration causes modest increase in enzyme activity
486697
2.3.1.26
7-oxocholesterol
-
720018
2.3.1.26
albumin
-
486676
,
486688
2.3.1.26
albumin
required in the assay medium to prevent the high concentration of oleoly-CoA from inhibiting the enzyme presumably by disrupting the microsomal membrane
486676
2.3.1.26
albumin
stimulates
486687
,
486688
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