EC Number |
Activating Compound |
Reference |
---|
2.2.1.1 | benfotiamine |
- |
695145 |
2.2.1.1 | benfotiamine |
not inhibitory on proliferation of insulinoma cell line INS-1. Treatment activates glucose metabolism in INS-1 cells in high-glucose culture conditions and maximizes the cells' ability to synthesize insulin. Treatment activates glucokinase |
695145 |
2.2.1.1 | cysteine |
activation, 10 mM |
486006 |
2.2.1.1 | ethanol |
activation, 1-10% v/v |
486006 |
2.2.1.1 | hydrogen peroxide |
oxidative stress increases tktA expression. Induces tktA at 1 h treatment, while an increase in marRAB operon expression occurs only after 3 h exposure |
694217 |
2.2.1.1 | more |
active centers of the enzyme are functionally nonequivalent with respect to ribose 5-phosphate binding |
690697 |
2.2.1.1 | more |
highest productivity unter slightly aerobic conditions |
704746 |
2.2.1.1 | more |
increased levels of TKTL1 transcript in tumors compared with their corresponding normal tissues. Positive correlation between TKTL1 protein expression in primary tumors and the number of metastatic lymph-nodes as well as the diameter of the largest metastatic area in lymph-nodes. High levels of TKTL1 transcript are a relevant phenomenon in small PTCs |
691583 |
2.2.1.1 | more |
positive transcriptional regulation of the talA-tktB operon by ppGpp |
694236 |
2.2.1.1 | more |
positive transcriptional regulation of the talA-tktB operon by ppGpp. Activation of tktB transcription by ppGpp occurs both through the modulation of RpoS levels and independent of RpoS |
694236 |