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EC Number
Activating Compound
Commentary
Reference
1.14.11.67
ascorbate
required
700164
,
746537
1.14.11.67
glycerol
50% increase of activity in the presence of 30% (v/v) glycerol as compared to that in the presence of 0-10% (v/v) glycerol
756031
1.14.11.67
histone H3
the in vitro demethylase activity of the enzyme is allosterically enhanced by binding of its product, unmodified histone H3 peptides, to its PHD1 reader domain
757752
1.14.11.67
more
interleukin-1beta enhances recruitment of LSD1 to mPGES-1 promoter
744188
1.14.11.67
N-oxalylglycine
required, essential for the demethylase activity in vivo
726261
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