EC Number   |
Activating Compound |
Reference |
|---|
   1.14.11.18 | 2-hydroxyphytanoyl-CoA |
- |
674512 |
| 1.14.11.18 | albumin |
0.05 mM 3-methylhexadecanoyl-CoA, no hydroxylation in absence of albumin. Hydroxylation of 3-methylnonanoyl-CoA or 3-methyldodecanoyl-CoA is much less dependent on the presence of albumin |
659665 |
| 1.14.11.18 | ascorbate |
2.5fold induction at 5 mM |
285267 |
| 1.14.11.18 | ascorbate |
at 1mM |
285264, 285271 |
| 1.14.11.18 | ATP |
at 0.1 mM Fe2+ 4 mM ATP inhibits enzyme activity. At increased Fe2+ concentrations ATP stimulates with a maximum at 64 mM ATP for 1.0 mM Fe2+ |
659669 |
| 1.14.11.18 | GTP |
at 0.1 mM Fe2+ 4 mM GTP inhibits enzyme activity. At increased Fe2+ concentrations ATP stimulates with a maximum at 64 mM GTP for 1.0 mM Fe2+ |
659669 |
| 1.14.11.18 | imidazole |
at 0.1 mM Fe2+ 4 mM ATP inhibits enzyme activity. At increased Fe2+ concentrations ATP stimulates with a maximum at 64 mM ATP for 1.0 mM Fe2+ |
659669 |
| 1.14.11.18 | imidazole |
stimulates at 1.0 mM Fe2+ |
659669 |
| 1.14.11.18 | SCP-2 |
phytanoylis efficiently 2-hydroxylated by PAHX in vitro in the presence of mature SCO-2. SCP-2 increases discrimination between straight-chain and branched-chain substrates, i.e. it decreases activity with straight chain substrates and increase activity with branched-chain substrates. In vivo substrates for PAHX may be SCP-2 complexes |
658428 |
