EC Number |
Activating Compound |
Reference |
---|
1.11.1.9 | cysteine |
cysteine increases activity at low glutathione concentrations |
688035 |
1.11.1.9 | EDTA |
2 mM, 128% of initial activity |
764056 |
1.11.1.9 | etoposide |
activates p53, wich induces the expression of glutathione peroxidase |
396631 |
1.11.1.9 | genistein |
- |
658933 |
1.11.1.9 | hyperglycemia |
increased GPX1 activity in rat VSM cell. When cells are exposed to high glucose (25 mM) for 48 h, GPX1 activity is 2.5fold greater than in cells grown in normal glucose (5 mM), while the GPX1 expression levels are the same |
702092 |
1.11.1.9 | more |
administration of lead acetate (100 and 1000 mg/l for 18 weeks) evokes increase of GPx activity in the kidney of female, but not male rats |
695410 |
1.11.1.9 | more |
Cd+- and Hg+-induced root growth inhibition is strongly correlated with increased glutathione peroxidase activity, a slight increase of glutathione peroxidase activity is observed after application of Pb2+, Ni2+, and Zn2+, while Co2+ does not affect glutathione peroxidase activity, GPX activity is not affected by cold, heat or drought treatment and only a slight increase is observed after salt or H2O2 treatment |
700785 |
1.11.1.9 | more |
increasing the cellular O-GlcNAcylation level enhances GPX1 activity |
702092 |
1.11.1.9 | more |
injection of the O-GlcNAcase inhibitor 1,2-dideoxy-2'-propyl-alpha-D-glucopyranoso-[2,1-d]-DELTA2'-thiazoline increases GPX1 activity in the mouse liver |
702092 |
1.11.1.9 | more |
neither prostate tissue nor serum selenium concentrations are associated with prostate glutathione peroxidase activity |
701039 |