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Results 1 - 10 of 23 > >>
EC Number Activating Compound Commentary Reference
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41ADP - 286775, 760834, 761502, 762451
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41ADP activates. Michaelis-Menten constant for DL-isocitrate is lowered 3.5-fold in the wild-type IDH. The substitution of asparagine for aspartate in alpha-mutant enzyme D181N, beta-subunit mutant enzyme D192N, and gamma-subunit mutant enzyme D190N abolishes this allosteric effect of ADP on Km 685154
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41ADP allosteric activation by ADP involving residue betaY126. In the presence of 1 mM ADP, the Km,isocitrate is reduced almost equally in the wild-type, 3.6fold, and the alphaY126E mutant, 4.3fold 712440
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41ADP allosteric regulation, determination of mol ADP bound to an enzyme tetramer of wild-type and mutant enzymes at different starting concentrations, overview 656189
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41ADP the alpha2betagamma heterotetramer and alphagamma heterodimer can be allosterically activated by ADP 762437
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41AMP - 286749, 286772, 654783
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41AMP activates ICDH-1 286776
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41AMP activation of the enzyme and reduction of enzyme inhibition by mitochondrial mRNA, highly enhanced by presence of isocitrate, complex formation, overview 654652
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41AMP allosteric activation 656052
Show all pathways known for 1.1.1.41Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.41AMP allosteric activation, binds to subunit IDH1 721433
Results 1 - 10 of 23 > >>