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Results 1 - 10 of 31 > >>
EC Number
Activating Compound
Commentary
Reference
2-chloro-2'-deoxyadenosine
-
amyloid beta1-42
the levels of activated caspase-2 in cultured hippocampal neurons significantly increase within 30 min of treatment with 0.003 mM amyloid beta1-42
ATM/ATR
caspase-2 is activated by ATM/ATR independently of p53 when Chk1 activity is repressed
caspase-10
is required for effective processing of caspase-2
CD95-death-inducing signaling complex
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cyclin D3
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lovastatin
0.05 mM for 24 h, increases caspase-2 gene expression
more
caspase-2 is activated by dimerization
more
caspase-2 is activated by proximity-induced oligomerization and trans-cleavage in vitro. Caspase-2 activation is possibly also mediated by caspase-8 in the death-inducing signaling complex
more
caspase-2 is rapidly activated by nerve growth factor deprivation
Results 1 - 10 of 31 > >>