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Results 1 - 7 of 7
EC Number
Activating Compound
Commentary
Reference
2-mercaptoethanol
required for maximal activity
angiotensin II
1.2-fold increased activity of calpain-1, influence in expression of calpain-1
Ca2+
required for activation of mu-calpain. Membrane-binding of mu-calpain is Ca2+-dependent. Membrane binding of mu-calpain is due to the exposed hydrophobic surface of the active site conformation and does not reduce the Ca2+ requirement for activation
endotoxin
treatment with 12 mg/kg endotoxin increases diaphragm calpain activity and active calpain I protein
more
HRSP12 (UK114) stimulates the hydrolysis activity of Calpain1
more
no influence on expression of calpain-1 by mechanical stimulation
NS5A protein
the nonstructural hepatitis C virus protein NS5Ais sufficient to activate a calpain 1
Results 1 - 7 of 7