EC Number |
Activating Compound |
Reference |
---|
2.1.1.137 | dithiothreitol |
weak activation |
485148 |
2.1.1.137 | glutathione |
a 4fold increase in glutathione concentration, 2 to 8 mM, leads to a 2fold increase in enzyme activity, reducing environment is required for enzyme activity |
485148 |
2.1.1.137 | L-cysteine |
activates stronger than glutathione |
485148 |
2.1.1.137 | dithiothreitol |
- |
485152, 733740 |
2.1.1.137 | glutathione |
- |
485152 |
2.1.1.137 | L-cysteine |
- |
485152 |
2.1.1.137 | GSH |
nonenzymatic generation of arsenic triglutathione from arsenite when GSH is present at concentrations 2 mM or higher. Methylation of arsenic is catalyzed by Cyt19 only when arsenic triglutathione is present in the reaction mixture |
657702 |
2.1.1.137 | dimethylselenoxide |
weak activator of recombinant As(III)-methyltransferase, weak inhibitor of arsenite methylation in hepatocytes |
658442 |
2.1.1.137 | trimethyl-selenonium iodide |
weak activator of recombinant As(III)-methyltransferase, weak inhibitor of arsenite methylation in hepatocytes |
658442 |
2.1.1.137 | trimethylselenonium iodide |
weak activator of recombinant As(III)-methyltransferase, weak inhibitor of arsenite methylation in hepatocytes |
658442 |