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Results 1 - 4 of 4
EC Number
Activating Compound
Commentary
Reference
1alpha,25-dihydroxyvitamin D3
renal 24-hydroxylase is significantly stimulated by 1alpha,25-dihydroxyvitamin D3 treatment in both normal and Hyp mice. In normal mice, 1alpha,25-dihydroxyvitamin D3 treatment is more effective than calcium in turning on 24-hydroxylase activity. In Hyp mice, treatment with calcium plus 1alpha,25-dihydroxyvitamin D3 results in a greater increase in 24-hydroxylase than treatment with either agent alone. 24-hydroxylase is 3fold, and 8fold greater in Hyp mice relative to normal treated with 1alpha,25-dihydroxyvitamin D3, and calcium plus 1alpha,25-dihydroxyvitamin D3, respectively
adrenodoxin
required for activity of the recombinant enzyme
adrenodoxin reductase
required for activity of the recombinant enzyme
calcitriol
calcitriol increases its own degradation in renal failure by increasing the enzymatic activity of 24-hydroxylase
Results 1 - 4 of 4