EC Number   |
Activating Compound |
Reference |
|---|
    1.13.11.34 | (13S)-hydroperoxy-9,11-octadecadienoic acid |
- |
687264 |
| 1.13.11.34 | 5-LOX activating protein |
- |
711661 |
| 1.13.11.34 | 7-thiaarachidonic acid |
- |
439460 |
| 1.13.11.34 | ATP |
- |
684399, 684672, 688512, 689872, 743614 |
| 1.13.11.34 | phosphatidylcholine |
- |
711134, 712666 |
| 1.13.11.34 | guanosine 5'-O-(3-thiotriphosphate) |
10fold stimulation of arachidonic acid oxidation at 0.0005-0.001 mM |
439445 |
| 1.13.11.34 | ATP-alphaS |
118% of the activation with ATP |
439464 |
| 1.13.11.34 | 5-lipoxygenase activating protein |
5-lipoxygenase activating protein is crucial for conversion of endogenous substrate by 5LO 5-lipoxygenase activating protein also stimulates the utilization of exogenous arachidonic acid, and greatly (190fold) stimulates utilization of (5Z,8Z,10E,12S,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid |
711100 |
| 1.13.11.34 | FLAP |
5-lipoxygenase-activating protein, exclusively located at the nuclear membrane |
741975 |
| 1.13.11.34 | FLAP |
5-lipoxygenase-activating protein. Inhibitor BRP-7 blocks 5-LOX co-localization with FLAP at the nuclear envelope in neutrophils |
742210 |
