EC Number   |
Activating Compound |
Reference |
|---|
    6.3.4.2 | GTP |
not essential, but acts as activator on the glutamine reaction, optimal activation at 1 mM |
648987 |
| 6.3.4.2 | GTP |
required as allosteric effector to promote reaction with glutamine as substrate, GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis |
648963 |
| 6.3.4.2 | GTP |
required as an allosteric effector to promote glutamine hydrolysis |
648962 |
| 6.3.4.2 | GTP |
required, activates |
690817 |
| 6.3.4.2 | GTP |
stimulates reaction with ATP, UTP and Gln |
660794 |
| 6.3.4.2 | GTP |
the binding of GTP to the allosteric site promotes coordination of the phosphorylation of UTP and hydrolysis of glutamine for optimal efficiency in CTP synthesis rather than just acting to increase the rate of glutamine hydrolysis itself |
648964 |
| 6.3.4.2 | guanosine 5'-tetraphosphate |
0 mM guanosine, kact: 4/sec, KA: 0.19 mM, Ki: 0.5 mM |
674909 |
| 6.3.4.2 | guanosine 5'-tetraphosphate |
the GTP analogue is capable of activating Gln-dependent CTP formation |
674909 |
| 6.3.4.2 | ITP |
0 mM guanosine, kact: 5.2/sec, KA: 2.9 mM, Ki: 4.5 mM |
674909 |
| 6.3.4.2 | ITP |
the GTP analogue is capable of activating Gln-dependent CTP formation |
674909 |
