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<< < Results 11 - 20 of 31 > >>
EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55more etoposide, staurosporine, pacritaxel and cyclohexamide treatment promotes exon 9-inclusion, increasing the ratio of caspase-2S to caspase-2L 665952
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55more genotoxic stress 665588
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55more heat shock, UV irradiation and anti-Fas treatment activate caspase-2 666419
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55more photodynamic treatment, incubation with zinc(II)-phthalocyanine (0.0005 mM and 0.001 mM)and irradiated with red light 665247
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55more the enzyme is activated during apoptosis by a caspase-3 (CPP32)-like protease. When cells are induced to undergo apoptosis, endogenous caspase-2 is first cleaved into three fragments of 32000-33000 Da and 14000 Da, which are then further processed into 18000 Da and 12000 Da active subunits 647763
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55more the topoisomerase-II inhibitor etoposide induces processing of procaspase-2 717457
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55more when protein kinase CK2 activity is low, procaspase-2 is dephosphorylated, dimerized, and activated in a PIDDosome-independent manner 664753
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55P53 p53 induces PIDD expression resulting in a feed-forward loop 717458
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55p53-induced protein with a death domain PIDD, caspase-2 is activated by the p53 target gene product PIDD, i.e. LRDD or leucine-rich repeats and death domain containing, in a complex called the caspase-2-PIDDosome 718112
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.55p53-inducible death domain-containing protein PIDD 663875
<< < Results 11 - 20 of 31 > >>