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EC Number
Activating Compound
Commentary
Reference
2.4.1.11
proline
increased uptake leads to activation
488450
2.4.1.11
propionate
significant activation
488450
2.4.1.11
relaxin
stimulation of activity. In patients with type 2 diabetes a significant decrease in glycogen synthase activity is accompanied by the decrease in the effect of peptides, giving the following order of their efficiency: insulin = IGF-1 > relaxin. In myometrium of pregnant women with gestational treated and untreated diabetes, glycogen synthase activity decreases, the effect of insulin is weaker, whereas the effects of relaxin and IGF-1 increase thus giving the following order of their efficiency: relaxin > IGF-1 > insulin. Insulin therapy of type 1 diabetes incompletely restores sensitivity of the enzymes to the peptide actions
702190
2.4.1.11
ribose 5-phosphate
stimulates interconversion of D to I form
488422
2.4.1.11
SO42-
stimulatory effect increases as the enzyme becomes more phosphorylated
488413
2.4.1.11
staurosporine
-
488450
2.4.1.11
xylitol
increase of activity
488450
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