3.4.22.55	D316A/D330A	abolishes auto-processing and reduces enzymatic activity dramatically, 840fold decrease in activity	664882	
3.4.22.55	additional information	caspase prodomain-DELTA25 mutant is slightly less effective than wild-type caspase-2, inducing cell death of about 70% of transfected cells. Caspase prodomain-DELTA25 mutant cannot kill due to its impaired nuclear localization	647762	
3.4.22.55	C320A	catalytic residue, inactive mutant enzyme	713154	
3.4.22.55	C303A	catalytically inactive	665588	
3.4.22.55	C320A	catalytically inactive	732048	
3.4.22.55	S139An	expression of mutant S139A leads to significantly enhanced growth rate of cells	732048	
3.4.22.55	C320A	forms a dimer only when cell are treated with DRB	664753	
3.4.22.55	D316A	fusion of the linker to the large subunit, toxic when expressed in yeast	664882	
3.4.22.55	D330A	fusion of the linker to the small subunit, slightly greater deleterious effect on enzyme activity than fusion to the large subunit (D316A), toxic when expressed in yeast	664882	
3.4.22.55	C303A	inactive	664882